Granulation

About us

The Technical Group of Granulation introduces excellent granulation technology used in various industries. The group plans and implements technical sessions to make innovations in one field applicable to another field. The granulation technology depends on human sensibility and experience. Hence, the policy of this group is to introduce the technology and the operation technique established by analyzing difficulties in practical operation, empirical approach and theories.

The group asks the following persons for cooperation in the group management. Mr. Akiyoshi Takaoka (; Kaken Pharmaceutical Co., Ltd.), Mr. Teruo Yoshida (Yoshida Consulting Office), Mr. Isao Sekiguchi (Honorary Professor in Chuo University), Mr. Nobuo Arai (Powder technology Center.

Current level of technology, trend and activities in future

Granulation is a unit operation for improving powder handling (segregation, compaction, flow, resolution, disintegration, transport, maintenance, etc.) and creating functionality to powders by morphology control. What are needed in granulation are as follows:
 Morphology design fitted to particle properties (size and shape of particles, inner and outer structure, composition, strength, etc.)
 Preparation of raw materials
 Selection of granulation method (growth, compaction and pattern of liquid droplet generation)
 Selection of operation which is optimal to evaluation of granulated products

Granulation, forms a final product or an intermediate product for bulk handling, its relationship with other unit operations becomes increasingly important. Also, due to the variety of functions to be given, for example, intelligent, biomimetic multifunctional particles having self-healing properties or biological functions, are required, and the formation of nano-particles in powder materials, soft matter raw materials, such as polymers, liquid crystals, colloids, biomolecule, and precise form control according to diversification of raw materials is important.
Therefore, with regard to the evaluation of the liquid crosslinking force in wet granulation, for example, the control area which is no longer covered by the simple geometrical approximation method increases, and analytical evaluation is forced with the progress of the simulation method. Many numerical visualizations of wet granulation growth phenomena that handle solid-liquid multiphase phenomena have also been reported, and applied to the granulation field.
Furthermore, the basic technology of granulation is also required for the production of various forms without being limited to the form of particles.
On the other hand, with the diversification of raw materials, for example, the occurrence of blockade in equipment and the necessity of basic physical property measurement have become apparent again. Along with diversification of raw materials, there is also a need to restructure the basic technology of granulation. In the construction of the process, continuous operation and circulating system are required, and a technology can monitor the growth process of granulated body in-line is necessary. We will provide the topic on “PAT. Granulation System Using Real Time Inline Monitoring” and lead to the progress of the granulation process construction.

Conductor

Coordinator Chuo University Faculty of Science and Engineering MURASE/Kazuo
Vice Coordinator Tokyo Metropolitan University TAKEI/Takashi
Representative Organizer DALTON CORPORATION KUWAHARA/Toshiyuki
Vice Representative Organizer NARA MACHINERY CO., LTD. IWAMATSU/Hidetoshi
Organizer DALTON CORPORATION KOIZUMI/Ichiro
EARTHTECHNICA CO., LTD. OOTA/Mikiko
FREUND CORPORATION KURITA/Yuji
KIKUSUI SEISAKUSHO LTD. ATAGI/Koichi
KURIMOTO, LTD. FUJII/Atsushi
LION CORPORATION KOBAYASHI/Daisuke
NIPPON EIRICH CO., LTD. OGAWA/Yoshiyasu
POWREX CORPORATION UCHIDA/Kazuhiro
Emeritus Organizer  Yoshihara Consulting Engineer Office YOSHIHARA/Ichirou