Particulate Modification

About us

The Technical Group of Particulate Modification started in 1985 to contribute mainly to the pharmaceutical field. Japanese particulate modification technology is at the top level in the world, particularly in processing and industrialization of nanoparticles. The following technologies are expected to be developed from this time.

  • Particulate modification focused on macroscopic environment of particle surface and surface boundary
  • Particulate modification controlling mutual interaction between particles
  • Particulate modification and equipment development aiming at energy saving and higher efficiency
  • Development of non-contact sensor and system sensing particle behavior and properties inside equipment

In addition, the group will study orally disintegrating tablets and product discrimination which are drawing great attention in the medical field today.

Current level of technology, trend and activities in future

  1. Attained level
    Particulate processing technology in Japan is at the world top-level, particularly in processing and particle design.
    In the future, safe handling of nano-materials and environment-friendly processing technology, development of highly functional and multifunctional particles will be required.
  2. Trend:
    ・Development of particulate processing technology using characteristics of particle surface and interface
    ・Development of particulate processing technology controlling mutual interaction between particles
    ・Development of particulate processing technology, particulate processing equipment, and pharmaceutical additives for energy saving and high efficiency
    ・Development of sensors and monitors that can detect particle behavior and physical properties inside particulate processing equipment without contact
    ・Development of unmanned modification processes and systems using the above devices
    ・Practical application of continuous manufacturing process of pharmaceuticals → In the Standard Formulation Research Forum, continuous granulation and tableting system have been the theme.
    ・At the PLCM study group, OD tablets and swallowing aids are attracting attention.
    ・Functionalization of micro and macro devices by controlling nanostructures
  3. Activities:
    ・Study and implementation of a training system to develop human resource who actively participates in the above activities and has the ability to open up new fields
    ・Globalization of factory tours and seminars, and establishment of global strategy
    ・Active participation in exhibitions and small symposia at industrial exhibitions organized by APPIE.
    ・Planning and organizing particle processing conferences and symposiums actively with the aim of assisting APPIE member companies in globalization centered on Asia
    ・Development of international exchange that benefits better in cooperation with other technical groups and other related academic societies and associations.

Conductor

Coordinator Gifu Pharmaceutical University,
Department of Drug Delivery Technology & Science,
Laboratory of Pharmaceutical Engineering
TAKEUCHI/Hirofumi
Vice Coordinator Meijo University IWAMOTO/Kiyoshi
Representative Organizer DALTON CORPORATION ASAI/Naochika
Vice Representative Organizer SHIN-ETSU CHEMICAL CO., LTD. ITO/Yuichi
POWREX CORPORATION NAGATO/Takuya
Organizer ASAHI KASEI CHEMICALS CORPORATION SAITO/Toru
FREUND CORPORATION TANAKA/Toshiya
HOSOKAWA MICRON CORPORATION YOKOYAMA/Hiroshi
KIKUSUI SEISAKUSHO LTD. SHIMADA/Satoshi
NARA MACHINERY CO., LTD. TANABE/Bunmei
TAKEDA PHARMACEUTICAL COMPANY, LTD. SATO/Yoshinobu
TOKUJU CORPORATION NAKAMURA/Toshiro
TSUMURA & CO. YOSHIMURA/Tomonari
OHKAWARA KAKOHKI CO., LTD. OKAWARA/Masaaki
OHKAWARA KAKOHKI CO., LTD. OKAWARA/Tomonao
SHIONOGI & CO., LTD. TOYODA/Toshitada
SPERA PHARMA, INC. FUKUTA/Makoto